The 24-year-old former Hills star wore a one shoulder number specially designed by Diesel and inspired by the event's sponsor, Skyy Vodka.
Her bronzed and fabulously toned body was accented with make up by makeup artist James Vincent.
The makeup theme for the show was bronzed skin, sheer lips, bronze smoky eyes using Make up For Ever.
Kristin's outfit was one of the four eye-catching pieces from Diesel and SKYY Vodka's Capsule swim suit Collection inspired by the vodka's iconic cobalt blue bottle and logo graphics.
The show was the opening act of the five day long Mercedes-Benz Fashion Week Swim 2012.
Kristin arrived at the Miami International Airport on Wednesday night, July 13 accompanied by pal Jack Ketsoyan.
"Getting ready for the @DieselUSA and @SKYYVodka fashion show in Miami, so excited to wear the first glass bikini!" Kristin tweeted before hitting the catwalk.
After the show, Kristin and Gossip Girl star Jessica Szohr attended SKYY Vodka's Official Kick-Off Party at the Raleigh Hotel.
"It went well! I was so nervous but its done!!! Party time!" Kristin tweeted after the show.
The five day long Mercedes-Benz Fashion Week Swim 2012 will run through July 18. Participating brands showcasing their swimwear include: White Sands Australia, Poko Pano, Beach Bunny Swimwear, Crystal Jin, L*Space by Monica Wise, Wildfox Swimwear, Caffé Swimwear, Dolores Cortés, Mara Hoffman Swim, Aqua Di Lara, Natori, A.Ché, Red Carter, Cia.Marítima, Luli Fama, Luxe by Lisa Vogel, Lisa Blue, Kooey Swimwear Australia, Nicolita and True Religion.